CWEA is governed by members from a range of public and private sector organisations representing CWEA's partners. Members in turn nominate Directors to the Board to determine and oversee the strategic direction of CWEA, as well as providing fiscal and legal oversight.
Following the Local Government. changes from 1st April 2009, the CWEA Board has changed to reflect these and now comprises:
| Chairman | Robert Davis | Cheshire & Warrington Economic Alliance |
| Deputy Chairman | Cllr Jamie Macrae | Cheshire East Council |
| Cllr Bob Barr | Warrington Borough Council | |
| Martyn Bracegirdle | Connexions Cheshire & Warrington | |
| Chris Brown | Visit Chester & Cheshire | |
| Liz Davis | Learning & Skills Council | |
| John Dunning | Cheshire Chamber Enterprises Ltd | |
| Andy Farrall | Warrington Borough Council | |
| Cllr Wesley Fitgerald | Cheshire East Council | |
| Christine Gaskell | Bentley Motors | |
| Lord Grantchester | Grantchester Farms | |
| Cllr Mike Jones | Cheshire West & Chester Council | |
| Cllr Ian Marks | Warrington Borough Council | |
| Cllr Allan McKie | Cheshire West & Chester Council | |
| John Nicholson | Cheshire East Council | |
| Steve Robinson | Cheshire West & Chester Council | |
| Nigel Schofield | Schofield Diamond Travel | |
| Prof Tim Wheeler | North West Universities Association | |
| David Horstead | CWEA Acting Chief Executive |